体外膜肺氧合在院内成人心源性休克和心脏骤停中的应用研究

隋明亮, 汤卫兵, 吴长江, 黄超发, 杨雅迪, 夏大梅

Application of extracorporeal membrane oxygenation to adults with cardiogenic shock and cardiac arrest in hospital

SUI Mingliang, TANG Weibing, WU Changjiang, HUANG Chaofa, YANG Yadi, XIA Damei

表3 住院病死率和ECMO撤机成功率的单因素Cox比例风险回归分析

Tab 3 Univariate Cox proportional hazard regression analysis of hospital mortality and ECMO withdrawal success rate

Item B S.E Wald P value HR (95.0% CI) Primary outcome Age 0.053 0.058 0.833 0.361 1.054 (0.941‒1.181) BMI -0.001 0.242 0.000 0.998 0.999 (0.621‒1.607) SOFA scores 0.011 0.064 0.027 0.868 1.011 (0.891‒1.147) ECMO tube placement time 0.032 0.028 1.358 0.244 1.033 (0.978‒1.091) D to I time -0.005 0.012 0.194 0.659 0.995 (0.972‒1.108) Lactic acid level before ECMO initiation -0.172 0.155 1.232 0.267 0.842 (0.622‒1.141) 24 h LCR after ECMO initiation 0.179 3.937 0.191 0.662 0.179 (0.001‒401.203) Combined IABP treatment -3.749 2.122 3.120 0.077 0.024 (0.000‒1.508) AKI (prior to ECMO initiation) 3.400 1.606 4.484 0.034 29.960 (1.288‒697.195) Postoperative infection 3.612 1.395 6.706 0.010 37.028 (2.406‒569.790) Postoperative bleeding 1.042 1.120 0.867 0.062 2.835 (0.316‒25.444) Postoperative limb ischemia 3.290 1.378 5.706 0.017 6.853 (1.805‒399.524) Previous underlying diseases 1.739 1.952 0.794 0.373 5.693 (0.124‒260.970) Secondary outcome Age -2.027 1.017 3.973 0.047 1.007 (0.973‒1.041) BMI -0.007 0.140 0.002 0.962 0.993 (0.755‒1.308) SOFA scores 0.067 0.080 0.760 0.401 1.069 (0.915‒1.250) ECMO tube placement time 0.019 0.035 0.287 0.592 1.019 (0.951‒1.092) D to I time 0.001 0.010 0.023 0.880 1.001 (0.982‒1.021) Lactic acid level before ECMO initiation -0.034 0.101 0.110 0.741 0.967 (0.793‒1.179) 24 h LCR after ECMO initiation -4.779 2.843 2.849 0.091 0.008 (0.000‒2.168) Combined IABP treatment 2.395 0.821 8.510 0.041 1.674 (1.164‒4.769) AKI (prior to ECMO initiation) -2.154 1.023 4.433 0.036 1.857 (1.105‒8.023) Postoperative infection 0.063 0.734 0.736 0.391 1.877 (0.445‒7.910) Postoperative bleeding -0.360 0.714 0.241 0.624 0.698 (0.166‒2.940) Postoperative limb ischemia 1.498 1.416 1.118 0.290 4.472 (0.279‒71.807) Previous underlying diseases 0.122 0.731 0.028 0.867 1.130 (0.270‒4.738)