乙型肝炎病毒感染者血清脂蛋白亚类及其组分的定量特征

易小璇, 胡森林, 孙阳, 黄庆霞, 唐惠儒

Quantitative characteristics of serum lipoprotein phenotypes for HBV patients

YI Xiaoxuan, HU Senlin, SUN Yang, HUANG Qingxia, TANG Huiru

图3 血清脂蛋白能区分HBV患者 Note： A. The ROC curves for HBV-infection. Five covariant included age, gender, hypertension, diabetes mellitus and coronary heart disease, and 6 lipoproteins included HDL4-PL, VLDL1-(PL/LP), VLDL1-(FC/LP), VLDL5-(TAG/LP), (VLDL+IDL)-PL and (VLDL+IDL)-TAG. B. 1H NMR signals for lipoproteins and their components. Red and blue lines represent HBsAg (-) and HBsAg (+) group, respectively. B. Lipoprotein metabolism associated with HBV-infection. LCAT—lecithin-cholesterol acyl transferase; CETP—cholesterol ester transfer protein; LPL—lipoprotein lipase; HTAGL—hepatic triacylglycerol lipase; LDLR—low-density lipoprotein receptor.

Fig 3 Lipoprotein phenotypes can differentiate HBV-infected patients from controls