2型糖尿病脑病小鼠海马中转录因子EB活性与自噬功能的变化

陈奕馨, 程丽珍, 林祎嘉, 苗雅

Change of transcription factor EB activity and autophagy in hippocampus of type 2 diabetic encephalopathy mice

CHEN Yixin, CHENG Lizhen, LIN Yijia, MIAO Ya

图3 2组小鼠海马APP、p-tau、tau和Aβ蛋白水平的比较 (n=10) Note： A. The Western blotting images of APP, p-tau and tau proteins in the hippocampi of mice in the two groups. B. Statistical histogram of the protein bands in the Western blotting analysis. C. The immunofluorescence images of Aβ protein in the hippocampi of mice in the two groups. D. Statistical histogram of the fluorescence intensity of Aβ. E. The immunofluorescence images of p-tau protein in the hippocampi of mice in the two groups. F. Statistical histogram of the fluorescence intensity of p-tau. ①P=0.004, ②P=0.000, ③P=0.032, ④P=0.003, compared with the CON group.

Fig 3 Comparison of APP, p-tau, tau and Aβ proteins in the hippocampi of mice between the two groups (n=10)