肝硬化患者胰岛素抵抗的临床分析
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石翠翠, 张洁, 黄鹤鸣, 桑玉尔, 李光明
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Clinical analysis of insulin resistance in liver cirrhosis patients
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SHI Cuicui, ZHANG Jie, HUANG Heming, SANG Yuer, LI Guangming
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表1 有无胰岛素抵抗2组之间临床资料的比较
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Tab 1 Comparison of basic information between the groups with and without insulin resistance
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Item | IR ≤ 1.64 (n=117) | IR > 1.64 (n=91) | P value |
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Age/year | 63.23±12.38 | 61.48±11.11 | 0.290 | BMI/(kg·m-2) | 22.05±3.50 | 25.64±3.65 | 0.000 | Male/n (%) | 74 (63.25) | 45 (49.45) | 0.049 | Smoke/n (%) | 42 (35.90) | 31 (34.07) | 0.880 | Alcohol/n (%) | 29 (24.79) | 22 (24.18) | >0.990 | T2DM/n (%) | 30 (25.64) | 44 (48.35) | 0.001 | Hypertension/n (%) | 28 (23.93) | 29 (31.87) | 0.210 | Child-Pugh grade | | | | Child-Pugh A/n(%) | 47 (40.17) | 49 (53.85) | 0.070 | Child-Pugh B /n(%) | 43 (36.75) | 32 (35.16) | 0.880 | Child-Pugh C/n(%) | 27 (23.08) | 10 (10.99) | 0.028 | Child-Pugh score | 7.63±2.20 | 6.93±1.99 | 0.020 | FBG/(mmol·L-1) | 5.44±1.71 | 7.58±3.24 | 0.000 | HbA1c/% | 5.43±1.02 | 6.54±2.31 | 0.000 | Fasting insulin/(mIU·L-1) | 4.06±1.87 | 12.32±8.39 | 0.000 | HOMA-IR | 0.94±0.39 | 4.25±4.51 | 0.000 | Complication | | | | EVB/n(%) | 51 (43.59) | 40 (43.96) | >0.990 | Ascites/n(%) | 78 (66.67) | 33 (36.26) | 0.000 | HE/n(%) | 7 (5.98) | 5 (5.49) | >0.990 |
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