术中使用小剂量右美托咪定对乳腺癌手术患者预后的影响
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杨笑萱, 朱珊, 钱程, 储晓英
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Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery
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YANG Xiaoxuan, ZHU Shan, QIAN Cheng, CHU Xiaoying
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表1 倾向性评分匹配前2组患者基线特征及围术期资料比较
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Tab 1 Comparison of baseline characteristics and perioperative data between the two groups before propensity score matching
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| Item | DEX group (n=385) | Control group (n=273) | P value |
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| Age/year | 54.5±0.6 | 52.1±0.7 | 0.004 | | BMI/(kg·m-2) | 23.2±0.2 | 23.3±0.2 | 0.002 | | Chemotherapy/n(%) | 259 (67.3) | 180 (65.9) | 0.742 | | Radiotherapy/n(%) | 176 (45.7) | 127 (46.5) | 0.871 | | Hormonal therapy/n(%) | 236 (61.3) | 177 (64.8) | 0.365 | | ER+/n(%) | 224 (58.2) | 171 (62.6) | 0.258 | | PR+/n(%) | 155 (40.3) | 140 (51.3) | 0.011 | | HER2+/n(%) | 94 (24.4) | 61 (22.3) | 0.576 | | Ki67/n(%) | 209 (54.3) | 151 (55.3) | 0.812 | | ASA classification/n(%) | | | 0.000 | | Ⅰ | 206 (53.5) | 91 (33.3) | | | Ⅱ | 179 (46.5) | 182 (66.7) | | | TMN stage/n(%) | | | 0.937 | | 0 | 50 (13.0) | 31 (11.4) | | | Ⅰ | 155 (40.3) | 106 (38.8) | | | ⅡA | 101 (26.2) | 77 (28.2) | | | ⅡB | 36 (9.3) | 28 (10.3) | | | Ⅲ | 43 (11.2) | 31 (11.4) | | | Type of surgery/n(%) | | | 0.891 | | Breast-conserving surgery | 111 (28.8) | 80 (29.3) | | | Mastectomy | 274 (71.2) | 193 (70.7) | | | Duration of anesthesia/min | 64.8±1.1 | 61.1±0.9 | 0.023 | | Remifentanil/μg | 707.7±17.2 | 692.6±19.6 | 0.563 | | Sufentanyl/μg | 34.5±0.5 | 34.2±0.6 | 0.638 | | Propofol/mg | 142.0±1.2 | 138.6±1.4 | 0.074 | | Cisatracurium/mg | 19.7±0.2 | 19.4±0.3 | 0.301 | | Inhalable anesthetic/n(%) | | | 0.169 | | Sevoflurane | 183 (47.5) | 115 (42.1) | | | Desflurane | 202 (52.5) | 158 (57.9) | | | VAS score when leaving PACU | 0.6±0.0 | 0.6±0.0 | 0.342 | | Propensity score | 0.31±0.08 | 0.25±0.06 | 0.006 |
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