术中使用小剂量右美托咪定对乳腺癌手术患者预后的影响
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杨笑萱, 朱珊, 钱程, 储晓英
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Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery
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YANG Xiaoxuan, ZHU Shan, QIAN Cheng, CHU Xiaoying
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表2 倾向性评分匹配后2组患者基线特征及围术期资料比较
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Tab 2 Comparison of baseline characteristics and perioperative data between the two groups after propensity score matching
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Item | DEX group (n=239) | Control group (n=239) | P value |
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Age/year | 54.3±0.8 | 52.9±0.8 | 0.212 | BMI/(kg·m-2) | 23.1±0.2 | 23.0±0.2 | 0.681 | Chemotherapy/n(%) | 168 (70.3) | 161 (67.4) | 0.548 | Radiotherapy/n(%) | 119 (49.8) | 108 (45.2) | 0.357 | Hormonal therapy/n(%) | 116 (48.5) | 109 (45.6) | 0.582 | ER+/n(%) | 125 (52.3) | 141 (59.0) | 0.174 | PR+/n(%) | 158 (66.1) | 140 (58.6) | 0.113 | HER2+/n(%) | 60 (25.1) | 58 (24.3) | 0.916 | Ki67/n(%) | 129 (54.0) | 141 (59.0) | 0.308 | ASA classification/n(%) | | | 0.082 | Ⅰ | 109 (45.6) | 129 (54.0) | | Ⅱ | 130 (54.4) | 110 (46.0) | | TMN stage/n(%) | | | 0.531 | 0 | 24 (9.9) | 21 (8.5) | | Ⅰ | 103 (43.3) | 100 (41.9) | | ⅡA | 75 (31.2) | 79 (33.1) | | ⅡB | 10 (4.3) | 12 (5.1) | | Ⅲ | 27 (11.1) | 27 (11.4) | | Type of surgery/n(%) | | | 0.176 | Breast-conserving surgery | 6 (25.8) | 58 (24.3) | | Mastectomy | 177 (74.2) | 181 (75.7) | | Duration of anesthesia/min | 64.6±1.3 | 62.2±1.0 | 0.162 | Remifentanil/μg | 680.5±20.7 | 704.7±21.6 | 0.416 | Sufentanyl/μg | 34.0±0.7 | 34.2±0.7 | 0.781 | Propofol/mg | 141.9±1.5 | 138.2±1.4 | 0.073 | Cisatracurium/mg | 19.4±0.3 | 19.1±0.3 | 0.367 | Inhalable anesthetic/n(%) | | | 0.564 | Sevoflurane | 83 (34.8) | 76 (32.1) | | Desflurane | 156 (65.2) | 163 (67.9) | | VAS score when leaving PACU | 0.6±0.0 | 0.7±0.1 | 0.125 | Propensity score | 0.29±0.07 | 0.30±0.06 | 0.331 |
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