术中使用小剂量右美托咪定对乳腺癌手术患者预后的影响
杨笑萱, 朱珊, 钱程, 储晓英

Effect of intraoperative use of low-dose dexmedetomidine on the prognosis of patients undergoing breast cancer surgery
YANG Xiaoxuan, ZHU Shan, QIAN Cheng, CHU Xiaoying
表2 倾向性评分匹配后2组患者基线特征及围术期资料比较
Tab 2 Comparison of baseline characteristics and perioperative data between the two groups after propensity score matching
ItemDEX group (n=239)Control group (n=239)P value
Age/year54.3±0.852.9±0.80.212
BMI/(kg·m-2)23.1±0.223.0±0.20.681
Chemotherapy/n(%)168 (70.3)161 (67.4)0.548
Radiotherapy/n(%)119 (49.8)108 (45.2)0.357
Hormonal therapy/n(%)116 (48.5)109 (45.6)0.582
ER+/n(%)125 (52.3)141 (59.0)0.174
PR+/n(%)158 (66.1)140 (58.6)0.113
HER2+/n(%)60 (25.1)58 (24.3)0.916
Ki67/n(%)129 (54.0)141 (59.0)0.308
ASA classification/n(%)0.082
109 (45.6)129 (54.0)
130 (54.4)110 (46.0)
TMN stage/n(%)0.531
024 (9.9)21 (8.5)
103 (43.3)100 (41.9)
ⅡA75 (31.2)79 (33.1)
ⅡB10 (4.3)12 (5.1)
27 (11.1)27 (11.4)
Type of surgery/n(%)0.176
Breast-conserving surgery6 (25.8)58 (24.3)
Mastectomy177 (74.2)181 (75.7)
Duration of anesthesia/min64.6±1.362.2±1.00.162
Remifentanil/μg680.5±20.7704.7±21.60.416
Sufentanyl/μg34.0±0.734.2±0.70.781
Propofol/mg141.9±1.5138.2±1.40.073
Cisatracurium/mg19.4±0.319.1±0.30.367
Inhalable anesthetic/n(%)0.564
Sevoflurane83 (34.8)76 (32.1)
Desflurane156 (65.2)163 (67.9)
VAS score when leaving PACU0.6±0.00.7±0.10.125
Propensity score0.29±0.070.30±0.060.331