Gender | Male | Male | Female | Male |
Age/year | 76 | 71 | 44 | 58 |
Brief history of illness | Progressive exophthalmos for 1 year, suspected of thyroid-associated ophthalmopathy | Swelling of the left upper eyelid for 5 months, slowly worsened | Bilateral upper eyelids swelling for 1 year, slowly worsened | Bilateral upper eyelids swelling for half a year (mainly the right), slowly worsened |
Sites of orbital involvement | Bilateral lacrimal glands, some extraocular muscles, optic nerve | Bilateral lacrimal glands (mainly the left) | Bilateral lacrimal glands | Bilateral lacrimal glands (mainly the right) |
Extraocular sites of involvement | Suspected submandibular gland lesions (resected in other hospital) | Submandibular gland enlargement, tonsillitis | Submandibular lymph nodes enlargement, pharyngitis | Sinusitis, left parotid gland lesion (partial resection) |
Pathology | No | No | No | IgG4-RD confirmed by another hospital |
Corrected visual acuity① (R/L) | 0.6/0.4 | 0.9/0.8 | 1.2/1.2 | 1.0/1.0 |
NCT (R/L)/ mmHg | 20.1/23.4 | 17.6/18.2 | 13.3/16.4 | 15.2/14.8 |
Conjunctiva | Hyperaemia (++), chemosis (+) | Hyperaemia (-) | Hyperaemia (-) | Hyperaemia (-) |
Anterior segment | Punctate epithelial erosions in the left, bilateral mild nuclear sclerosis | Bilateral mild nuclear sclerosis | (-) | (-) |
Optic disc | Swelling | (-) | (-) | (-) |
Macula | (-) | (-) | (-) | (-) |
Exophthalmus (R/L)/mm | 21/23 | 15/16 | 18/18 | 17/15 |
Serum IgG4/(g·L-1)② | 24.10 | 28.90 | 4.10 | 14.40 |
Serum IgG/(g·L-1)③ | 29.00 | 18.10 | 12.20 | 26.70 |
IgG4-RD RI | 10 | 6 | 6 | 6 |