眶内注射复方倍他米松治疗IgG4相关性眼病的效果观察
刘小红, 王亚娜, 焦秦, 程瑜

Observation on the therapeutic effect of intraorbital injection of compound betamethasone on the treatment of IgG4-related ophthalmic disease
LIU Xiaohong, WANG Yanuo, JIAO Qin, CHENG Yu
表1 4IgG4-ROD患者初始状况
Tab 1 Initial characteristics of 4 patients with IgG4-ROD
ItemCase 1Case 2Case 3Case 4
GenderMaleMaleFemaleMale
Age/year76714458
Brief history of illnessProgressive exophthalmos for 1 year, suspected of thyroid-associated ophthalmopathySwelling of the left upper eyelid for 5 months, slowly worsenedBilateral upper eyelids swelling for 1 year, slowly worsenedBilateral upper eyelids swelling for half a year (mainly the right), slowly worsened
Sites of orbital involvementBilateral lacrimal glands, some extraocular muscles, optic nerveBilateral lacrimal glands (mainly the left)Bilateral lacrimal glandsBilateral lacrimal glands (mainly the right)
Extraocular sites of involvementSuspected submandibular gland lesions (resected in other hospital)Submandibular gland enlargement, tonsillitisSubmandibular lymph nodes enlargement, pharyngitisSinusitis, left parotid gland lesion (partial resection)
PathologyNoNoNoIgG4-RD confirmed by another hospital

Corrected visual

acuity (R/L)

0.6/0.40.9/0.81.2/1.21.0/1.0
NCT (R/L)/ mmHg20.1/23.417.6/18.213.3/16.415.2/14.8
ConjunctivaHyperaemia (++), chemosis (+)Hyperaemia (-)Hyperaemia (-)Hyperaemia (-)
Anterior segmentPunctate epithelial erosions in the left, bilateral mild nuclear sclerosisBilateral mild nuclear sclerosis(-)(-)
Optic discSwelling(-)(-)(-)
Macula(-)(-)(-)(-)
Exophthalmus (R/L)/mm21/2315/1618/1817/15
Serum IgG4/(g·L-124.1028.904.1014.40
Serum IgG/(g·L-129.0018.1012.2026.70
IgG4-RD RI10666