线粒体内膜转位酶8A基因敲除小鼠的构建及其内耳功能研究

洪晗馨, 王龙昊, 刘辉辉, 彭浒, 吴皓, 杨涛

Construction of translocase of inner mitochondrial membrane 8A gene knockout mice and study of its inner ear function

HONG Hanxin, WANG Longhao, LIU Huihui, PENG Hu, WU Hao, YANG Tao

图2 Timm8a^-^/^- 小鼠构建的验证及其与WT小鼠的体型观察
Note： A/B. Identification of Timm8a loxP (A) and ACTB-Cregenotype (B) of mice by PCR amplification. 421 bp is band of Timm8a loxP band, 361 bp is WT band, 100 bp is Cre positive band, 324 bp is positive control band. C. Detection of TIMM8A in different tissues of Timm8a^-^/- mice and WT mice by Western blotting. D. Comparison of body size between Timm8a^-^/- mice and WT mice. E. Comparison of weight between Timm8a^-/- mice and WT mice.

Fig 2 Verification of Timm8a^-^/- mouse construction and observation of its body size with WT mice