放疗对行化疗和手术的直肠癌患者的效果分析：一项基于SEER数据库的回顾性研究
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王安君, 刘宁宁
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Efficacy of radiotherapy in patients with rectal cancer undergoing chemotherapy and surgery: a retrospective study based on the SEER database
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WANG Anjun, LIU Ningning
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表1 PSM前后RT+S组和S组直肠癌患者的临床基本特征
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Tab 1 Basic characteristics of rectal cancer patients in the RT+S group and the S group before and after PSM
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| Characteristic | Before PSM | After PSM |
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All (n=7 070) | S group (n=1 079) | RT+S group (n=5 991) | P value | All (n=1 906) | S group (n=953) | RT+S group (n=953) | P value |
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| Age/n (%) | | | | 0.024 | | | | 0.999 | | <50 years | 1 606 (22.7) | 216 (20.0) | 1 390 (23.2) | | 371 (19.5) | 185 (19.4) | 186 (19.5) | | | ≥50 years | 5 464 (77.3) | 863 (80.0) | 4 601 (76.8) | | 1 535 (80.5) | 768 (80.6) | 767 (80.5) | | | Gender/n (%) | | | | 0.049 | | | | 0.999 | | Male | 4 412 (62.4) | 644 (59.7) | 3 768 (62.9) | | 1 129 (59.2) | 564 (59.2) | 565 (59.3) | | | Female | 2 658 (37.6) | 435 (40.3) | 2 223 (37.1) | | 777 (40.8) | 389 (40.8) | 388 (40.7) | | | Race/n (%) | | | | 0.063 | | | | 0.294 | | White | 5 414 (76.6) | 818 (75.8) | 4 596 (76.7) | | 1 416 (74.3) | 699 (73.3) | 717 (75.2) | | | Black | 524 (7.4) | 98 (9.1) | 426 (7.1) | | 165 (8.7) | 79 (8.3) | 86 (9.0) | | | Others | 1 132 (16.0) | 163 (15.1) | 969 (16.2) | | 325 (17.1) | 175 (18.4) | 150 (15.7) | | | Marital status/n (%) | | | | 0.681 | | | | 0.541 | | Married | 4 183 (59.2) | 645 (59.8) | 3 538 (59.1) | | 1 172 (61.5) | 593 (62.2) | 579 (60.8) | | | Others | 2 887 (40.8) | 434 (40.2) | 2 453 (40.9) | | 734 (38.5) | 360 (37.8) | 374 (39.2) | | | Tumor histology/n (%) | | | | 0.000 | | | | 0.956 | | Adenocarcinoma | 5 734 (81.1) | 815 (75.5) | 4 919 (82.1) | | 1 472 (77.2) | 737 (77.3) | 735 (77.1) | | | Others | 1 336 (18.9) | 264 (24.5) | 1 072 (17.9) | | 434 (22.8) | 216 (22.7) | 218 (22.9) | | | Tumor size/n (%) | | | | 0.010 | | | | 0.999 | | ≤30 mm | 1 586 (22.4) | 228 (21.1) | 1 358 (22.7) | | 410 (21.5) | 205 (21.5) | 205 (21.5) | | | >30‒50 mm | 3 312 (46.8) | 477 (44.2) | 2 835 (47.3) | | 878 (46.1) | 439 (46.1) | 439 (46.1) | | | >50 mm | 2 172 (30.7) | 374 (34.7) | 1 798 (30.0) | | 618 (32.4) | 309 (32.4) | 309 (32.4) | | | Histologic grade/n (%) | | | | 0.000 | | | | 0.970 | | Well differentiated | 445 (6.3) | 43 (4.0) | 402 (6.7) | | 70 (3.7) | 34 (3.6) | 36 (3.8) | | | Moderately differentiated | 5 549 (78.5) | 806 (74.7) | 4 743 (79.2) | | 1 463 (76.8) | 732 (76.8) | 731 (76.7) | | | Poorly differentiated/undifferentiated | 1 076 (15.2) | 230 (21.3) | 846 (14.1) | | 373 (19.6) | 187 (19.6) | 186 (19.5) | | | TNM stage/n (%) | | | | 0.000 | | | | 0.999 | | Ⅰ | 677 (9.6) | 50 (4.6) | 627 (10.5) | | 93 (4.9) | 46 (4.8) | 47 (4.9) | | | Ⅱ | 2 027 (28.7) | 144 (13.3) | 1 883 (31.4) | | 288 (15.1) | 145 (15.2) | 143 (15.0) | | | Ⅲ | 3 509 (49.6) | 480 (44.5) | 3 029 (50.6) | | 947 (49.7) | 473 (49.6) | 474 (49.7) | | | Ⅳ | 857 (12.1) | 405 (37.5) | 452 (7.5) | | 578 (30.3) | 289 (30.3) | 289 (30.3) | | | Regional nodes examined/n (%) | | | | 0.000 | | | | 0.999 | | <12 | 3 065 (43.4) | 411 (38.1) | 2 654 (44.3) | | 734 (38.5) | 367 (38.5) | 367 (38.5) | | | ≥12 | 4 005 (56.6) | 668 (61.9) | 3 337 (55.7) | | 1 172 (61.5) | 586 (61.5) | 586 (61.5) | |
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