放疗对行化疗和手术的直肠癌患者的效果分析:一项基于SEER数据库的回顾性研究
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王安君, 刘宁宁
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Efficacy of radiotherapy in patients with rectal cancer undergoing chemotherapy and surgery: a retrospective study based on the SEER database
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WANG Anjun, LIU Ningning
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表2 PSM前后S组和S+RT组直肠癌患者的临床基本特征
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Tab 2 Basic characteristics of rectal cancer patients in the S group and the S+RT group before and after PSM
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Characteristic | Before PSM | After PSM |
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All (n=2 984) | S group (n=1 079) | S+RT group (n=1 905) | P value | All (n=1 478) | S group (n=739) | S+RT group (n=739) | P value |
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Age/n (%) | | | | 0.344 | | | | 0.842 | <50 years | 569 (19.1) | 216 (20.0) | 353 (18.5) | | 278 (18.8) | 137 (18.5) | 141 (19.1) | | ≥50 years | 2 415 (80.9) | 863 (80.0) | 1 552 (81.5) | | 1 200 (81.2) | 602 (81.5) | 598 (80.9) | | Gender/n (%) | | | | 0.473 | | | | 0.874 | Male | 1 754 (58.8) | 644 (59.7) | 1 110 (58.3) | | 862 (58.3) | 429 (58.1) | 433 (58.6) | | Female | 1 230 (41.2) | 435 (40.3) | 795 (41.7) | | 616 (41.7) | 310 (41.9) | 306 (41.4) | | Race/n (%) | | | | 0.531 | | | | 0.231 | White | 2 274 (76.2) | 818 (75.8) | 1 456 (76.4) | | 1 120 (75.8) | 550 (74.4) | 570 (77.1) | | Black | 249 (8.3) | 98 (9.1) | 151 (7.9) | | 122 (8.3) | 59 (8.0) | 63 (8.5) | | Others | 461 (15.4) | 163 (15.1) | 298 (15.6) | | 236 (16.0) | 130 (17.6) | 106 (14.3) | | Marital status/n (%) | | | | 0.655 | | | | 0.264 | Married | 1 801 (60.4) | 645 (59.8) | 1 156 (60.7) | | 892 (60.4) | 435 (58.9) | 457 (61.8) | | Others | 1 183 (39.6) | 434 (40.2) | 749 (39.3) | | 586 (39.6) | 304 (41.1) | 282 (38.2) | | Tumor histology/n (%) | | | | 0.012 | | | | 0.859 | Adenocarcinoma | 2 171 (72.8) | 815 (75.5) | 1 356 (71.2) | | 1 092 (73.9) | 544 (73.6) | 548 (74.2) | | Others | 813 (27.2) | 264 (24.5) | 549 (28.8) | | 386 (26.1) | 195 (26.4) | 191 (25.8) | | Tumor size/n (%) | | | | 0.000 | | | | 0.970 | ≤30 mm | 792 (26.5) | 228 (21.1) | 564 (29.6) | | 370 (25.0) | 185 (25.0) | 185 (25.0) | | >30‒50 mm | 1 295 (43.4) | 477 (44.2) | 818 (42.9) | | 670 (45.3) | 333 (45.1) | 337 (45.6) | | >50 mm | 897 (30.1) | 374 (34.7) | 523 (27.5) | | 438 (29.6) | 221 (29.9) | 217 (29.4) | | Histologic grade/n (%) | | | | 0.008 | | | | 0.999 | Well differentiated | 154 (5.2) | 43 (4.0) | 111 (5.8) | | 54 (3.7) | 27 (3.7) | 27 (3.7) | | Moderately differentiated | 2 263 (75.8) | 806 (74.7) | 1 457 (76.5) | | 1 154 (78.1) | 577 (78.1) | 577 (78.1) | | Poorly differentiated/undifferentiated | 567 (19.0) | 230 (21.3) | 337 (17.7) | | 270 (18.3) | 135 (18.3) | 135 (18.3) | | TNM stage/n (%) | | | | 0.000 | | | | 0.999 | Ⅰ | 309 (10.4) | 50 (4.6) | 259 (13.6) | | 82 (5.6) | 41 (5.6) | 41 (5.6) | | Ⅱ | 618 (20.7) | 144 (13.3) | 474 (24.9) | | 266 (18.0) | 133 (18.0) | 133 (18.0) | | Ⅲ | 1 533 (51.4) | 480 (44.5) | 1 053 (55.3) | | 922 (62.4) | 461 (62.4) | 461 (62.4) | | Ⅳ | 524 (17.6) | 405 (37.5) | 119 (6.3) | | 208 (14.1) | 104 (14.1) | 104 (14.1) | | Regional nodes examined/n (%) | | | | 0.799 | | | | 0.999 | <12 | 1 147 (38.4) | 411 (38.1) | 736 (38.6) | | 522 (35.3) | 261 (35.3) | 261 (35.3) | | ≥12 | 1 837 (61.6) | 668 (61.9) | 1 169 (61.4) | | 956 (64.7) | 478 (64.7) | 478 (64.7) | |
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