蓝藻丝氨酸蛋白酶抑制剂arthropin的制备及其靶蛋白酶的筛选

许佳伟, 周爱武, 杨愈丰

Preparation and target protease identification of a cyanobacterial serine protease inhibitor, arthropin

XU Jiawei, ZHOU Aiwu, YANG Yufeng

图1 Arthropin与多种serpin的RCL序列比对 Note：α1-AT—α1-antitrypsin (Uniprot ID: A0A024R6I7); KAL—kallistatin (Uniprot ID: P29622); PN1—protein nexin 1 (Uniprot ID: P07093); miropin (Uniprot ID: G8UQY8); siropin (UniProt ID: R6RSK2); arthropin (GenBank ID: AMW27298.1). s1C—strand 1 of β-sheet C.

Fig 1 RCL sequence comparison of arthropin with various serpins