早中期早产儿校正18月龄神经发育状况和影响因素

沈力, 黄亨烨, 于广军

Current status of neurodevelopmental outcomes and its influencing factors of early-to-moderate preterm infants at corrected age of 18 months

SHEN Li, HUANG Hengye, YU Guangjun

表2 神经发育正常组和迟缓组早产儿父母临床指标比较

Tab 2 Comparison of clinical variables for parents of preterm infants between the normal neurodevelopment group and the neurodevelopmental retardation group

Variable Total (n=929) Normal neurodevelopment group (n=782) Neurodevelopmental retardation group (n=147) z/χ2 value P value Maternal age/year 31.0 (28.0, 34.0) 31.0 (28.0, 34.0) 31.0 (28.0, 34.0) 0.161 0.872 Parental smoking①/n(%) 179 (19.3) 145 (18.5) 34 (23.1) 1.674 0.196 Maternal alcohol consumption/n(%) 4 (0.4) 4 (0.5) 0 (0) 0.755 0.855 Father's chronic illness/n(%) 33 (3.6) 25 (3.2) 8 (5.4) 1.821 0.177 Mother's chronic illness/n(%) 43 (4.6) 34 (4.3) 9 (6.1) 0.883 0.347 Gestational hypertension/n(%) 48 (5.2) 37 (4.7) 11 (7.5) 1.912 0.167 Gestational diabetes mellitus/n(%) 95 (10.2) 76 (9.7) 19 (12.9) 1.386 0.239 Thyroid disease during pregnancy/n(%) 44 (4.7) 33 (4.2) 11 (7.5) 2.920 0.087 Anemia during pregnancy/n(%) 36 (3.9) 27 (3.5) 9 (6.1) 2.368 0.124 Placenta previa/n(%) 15 (1.6) 14 (1.8) 1 (0.7) 0.388 0.533 Abruptio placentae/n(%) 9 (1.0) 9 (1.2) 0 (0) 0.719 0.396 Abnormal fetal position/n(%) 5 (0.5) 5 (0.6) 0 (0) 0.128 0.721 Number of prenatal tests≥8/n(%) 363 (39.1) 307 (39.3) 56 (38.1) 0.070 0.791 Tertiary hospital maternity examination/n(%) 401 (43.2) 331 (42.3) 70 (47.6) 1.412 0.235