| Item | Massive bleeding group (n=215) | Non-massive bleeding group (n=24) | Z/χ2 value | P value |
|---|
| Gender/n(%) | | | 0.941 | 0.332 | | Male | 140 (65.1) | 18 (75.0) | | | | Female | 75 (34.9) | 6 (25.0) | | | | Age/month | 11 (7, 21) | 22 (10, 30) | -2.301 | 0.021 | | Weight/kg | 9.6 (8.4, 11.0) | 12.0 (10.1, 13.8) | -3.089 | 0.002 | | Body length/cm | 75 (70, 82) | 85 (74, 94) | -3.436 | 0.001 | | Previous craniofacial surgery/n(%) | 14 (6.5) | 3 (12.5) | 1.172 | 0.507 | | Syndromic/n(%) | 12 (5.6) | 1 (4.2) | 0.084 | 0.772 | | Hydrocephalus/n(%) | 10 (4.7) | 0 (0) | 1.165 | 0.590 | | Family history/n(%) | 2 (0.9) | 0 (0) | 0.225 | 0.642 | | Duration of symptom/month | 9 (6, 17) | 14 (6, 24) | -1.901 | 0.057 | | Preoperative Hb/(g·L-1) | 121 (113, 126) | 125 (116, 130) | -1.369 | 0.171 | | Preoperative hematocrit/% | 36.45 (38.00, 34.10) | 37.20 (38.90, 35.30) | -1.664 | 0.096 | | Preoperative albumin/(g·L-1) | 41.4 (39.5, 44.2) | 42.7 (39.9, 44.0) | -0.584 | 0.559 | | Lowest temperature in operation/℃ | 35.6 (35.0, 36.1) | 36.1 (35.2, 36.4) | -2.131 | 0.033 | | Duration of surgery/min | 215.5 (184.0, 243.0) | 216.0 (176.0, 251.0) | -0.367 | 0.713 | | Amount of crystalloid and colloids infusion/mL | 350 (200, 500) | 400 (263, 575) | -0.763 | 0.446 | | Amount of blood products using | | | | | | RBC transfusion/mL | 300 (200, 300) | 150 (150, 300) | -3.169 | 0.002 | | Plasma transfusion/mL | 100 (0, 100) | 100 (0, 100) | -1.506 | 0.132 | | FFP/n(%) | 7 (3.3) | 0 (0) | 1.430 | 1.000 | | Cryoprecipitate/n(%) | 8 (3.7) | 0 (0) | 0.924 | 1.000 | | Use of hemostatic drugs/n(%) | | | | | | Hemocoagulase injection | 111 (5.2) | 8 (3.3) | 2.890 | 0.089 | | Tranexamic acid | 18 (8.3) | 0 (0) | 2.173 | 0.140 | | PPSB | 13 (6.0) | 0 (0) | 1.535 | 0.373 | | Number of sutures/n(%) | | | 4.148 | 0.126 | | 1 | 134 (62.3) | 10 (45.8) | | | | 2 | 64 (29.8) | 12 (50.0) | | | | ≥3 | 17 (7.9) | 1 (4.2) | | | | Craniosynostosis type/n(%) | | | 13.268 | 0.010 | | Scaphocephaly | 64 (29.8) | 6 (25.0) | | | | Brachycephaly | 16 (7.4) | 2 (8.3) | | | | Trigonocephaly | 39 (18.1) | 3 (12.5) | | | | Plagiocephaly | 17 (7.9) | 1 (4.2) | | | | Multiple | 79 (36.7) | 12 (50.0) | | | | Type of operation/n(%) | | | 8.482 | 0.033 | | CVR | 117 (54.5) | 15 (62.5) | | | | FOA | 8 (3.7) | 2 (8.3) | | | | CVR＋FOA | 87 (40.5) | 5 (20.8) | | | | Others | 3 (1.4) | 2 (8.3) | | |
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