赖氨酸去甲基化酶5C对肾癌转移的作用研究

陈宁黛, 周冰倩, 陈哲逸, 陈诗宇, 郑英霞

Effect of lysine demethylase 5C on renal carcinoma metastasis

CHEN Ningdai, ZHOU Bingqian, CHEN Zheyi, CHEN Shiyu, ZHEN Yingxia

图3 KDM5C 敲除后肾癌细胞的RNA测序 Note： A. PCA plot and heatmap of the two groups. B. Venn plots of upregulated and downregulated genes in 786-O_KDM5C-sg cells compared to 786-O_-control-sg cells. C/D. Go analysis (C) and KEGG analysis (D) on the sequencing data. E. KM plot of the prognosis of KIRC patients with and without KDM5C mutation.

Fig 3 RNA sequencing analysis of renal carcinoma cells with KDM5C knockout