赖氨酸去甲基化酶5C对肾癌转移的作用研究

陈宁黛, 周冰倩, 陈哲逸, 陈诗宇, 郑英霞

Effect of lysine demethylase 5C on renal carcinoma metastasis

CHEN Ningdai, ZHOU Bingqian, CHEN Zheyi, CHEN Shiyu, ZHEN Yingxia

图5 KDM5C 敲除后上调的EMT相关基因对预后的影响 Note： A. Venn plot showed the common genes of survival analysis (P<0.01) and cox proportional-hazards model (P<0.01). B. KM plots showed the prognosis of 10 common genes in the TCGA database. C. LASSO coefficient profiles of genes significantly associated with OS. D. The forest plots showed the univariate COX analysis of the four genes significantly associated with OS.

Fig 5 Effect of up-regulated EMT-related gene on prognosis after KDM5C knockout