ZNF384融合亚型急性白血病的发病机制及预后研究进展

李瑛, 谭阳霞, 尹虹心, 蒋雁翎, 陈立, 蒙国宇

Research progress in the pathogenesis and prognosis of ZNF384 fusion subtype acute leukemia

LI Ying, TAN Yangxia, YIN Hongxin, JIANG Yanling, CHEN Li, MENG Guoyu

图2 ZNF384 部分融合亚型的断点统计以及融合蛋白结构图 Note： The exon6/6-exon2/3 on the left side of the figure indicates that there are two types of fusion breakpoints between EP300 and ZNF384, exon6-exon2 and exon6-exon3. The small colored squares below the figure represent protein domains. TAZ1—transcriptional adapter zinc binding 1.

Fig 2 Breakpoint statistics and fusion protein structure diagram of some ZNF384 fusion subtypes