RBX1通过STAT1调控葡萄膜黑色素瘤免疫相关基因 |
周晓雯, 李倩, 张哲, 沈键锋, 范先群 |
RBX1 regulates uveal melanoma immune-related genes via STAT1 |
ZHOU Xiaowen, LI Qian, ZHANG Zhe, SHEN Jianfeng, FAN Xianqun |
图1 RBX1 在肿瘤中的表达水平及对患者生存的影响 Note: A. Search for RBX1 expression in different tumors in GEPIA database. B. Overall survival heat map (above) and disease free survival heat map (below) of RBX1 in patients with various tumors. TPM—transcript per million; ACC—adrenocortical carcinoma; BLCA—bladder urothelial carcinoma; BRCA—breast invasive carcinoma; CESC—cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL—cholangiocarcinoma; COAD—colon adenocarcinoma; DLBC—lymphoid neoplasm diffuse large B-cell lymphoma; ESCA—esophageal carcinoma; GBM—glioblastoma multiforme; HNSC—head and neck squamous cell carcinoma; PAAD—pancreatic adenocarcinoma; PRAD—prostate adenocarcinoma; READ—rectum adenocarcinoma; SARC—sarcoma; SKCM—skin cutaneous melanoma; STAD—stomach adenocarcinoma; TGCT—testicular germ cell tumor; THYM—thymoma; UCEC—uterine corpus endometrial carcinoma; UCS—uterine carcinosarcoma; PCPG—pheochromocytoma and paraganglioma; KICH—kidney chromophobe; KIRC—kidney renal clear cell carcinoma; KIRP—kidney renal papillary cell carcinoma; LAML—acute myeloid leukemia; LGG—brain lower grade glioma; LIHC—liver hepatocellular carcinoma; LUAD—lung adenocarcinoma; LUSC—lung squamous cell carcinoma; MESO—mesothelioma; OV—ovarian serous cystadenocarcinoma; THCA—thyroid carcinoma; UVM—uveal melanoma. |
Fig 1 Expression of RBX1 in tumors and its effect on patients' survival |