基于生物学分析构建及验证棕榈酰化相关酶长链非编码RNA的肝癌预后风险模型

于莉, 苏显都, 张敏, 李雅慧, 王乐

Construction and validation of prognostic risk model for hepatocellular carcinoma based on biological analysis of palmitoyl-associated enzyme long-chain non-coding RNA

YU Li, SU Xiandu, ZHANG Min, LI Yahui, WANG Le

图1 影响肝癌患者预后的相关lncRNA单因素分析 Note： A/B. Expression of ZDHHCs [ZDHHC1?ZDHHC9 and ZDHHC11?ZDHHC12 (A), and ZDHHC13?ZDHHC24 (B)] in hepatocellular carcinomas (n=370) and normal liver tissues (n=50). *P<0.05. C. Kaplan-Meier survival analysis and Log-Rank test were performed on different ZDHHCs. The median of the high-risk and low-risk groups (n=185) was taken as the cutoff. D. ZDHHC-related lncRNA. E. Univariate Cox regression analysis to screen prognostic lncRNAs associated with ZDHHC.

Fig 1 Univariate analysis of associated lncRNAs affecting prognosis in patients with hepatocellular carcinoma