AAK1相互作用蛋白的筛选及其调控细胞内整体翻译水平的研究

姜贵先, 胡荣贵, 吴皓

Screening of AAK1 interaction proteins and its role in regulating global translation level in cells

JIANG Guixian, HU Ronggui, WU Hao

图4 通过嘌呤霉素结合实验验证AAK1对细胞内整体翻译水平的调控作用 Note： A. Transient overexpression of FMRP-down-regulated global protein synthesis in cells. B. Transient interference of FMRP with siRNA-up-regulated global protein synthesis in cells. C. Transient overexpression of AAK1-up-regulated global protein synthesis in cells. D. Transient interference of AAK1 with siRNA-down-regulated global protein synthesis in cells.

Fig 4 Verification of AAK1 regulation on protein synthesis in cells by puromycin incorporation assays