脑卒中后脑血管内皮细胞内质网应激抑制Wnt7/β-catenin通路导致血脑屏障损伤的机制研究

董海平, 谢海怡, 马晓晓, 王震虹

Mechanism of blood-brain barrier damage caused by the inhibition of Wnt7/β-catenin pathway induced by endoplasmic reticulum stress in cerebrovascular endothelial cells after stroke

DONG Haiping, XIE Haiyi, MA Xiaoxiao, WANG Zhenhong

图4 抑制内质网应激对OGD后HBMEC内Wnt7/β-catenin信号的影响 Note： A. Wnt7 and β-catenin protein expression bands. B. Analysis of Wnt7 protein expression in HBMECs. C. Analysis of β-catenin protein expression in HBMECs. ①P=0.000, ③P=0.002, compared with the Blank group; ②P=0.000, ④P=0.023, compared with the OGD group.

Fig 4 Effect of inhibiting endoplasmic reticulum stress on Wnt7/β-catenin signaling in HBMECs after OGD