小鼠输卵管上皮类器官的构建及表型验证

吴其谦, 胡燕琴, 陈迦勒, 李牧辰, 赵有淦, 伍静文

Establishment and phenotype verification of mouse oviductal epithelial organoids

WU Qiqian, HU Yanqin, CHEN Jiale, LI Muchen, ZHAO Yougan, WU Jingwen

图5 输卵管上皮类器官的细胞构成 Note： A/B. Co-immunofluorescent staining of Ac-α-tubulin (showing ciliated cells) and PAX8 (showing secretory cells) in the organoid sections (A) and the oviducts (B) of WT mice and dKO mice (×400, scale bar=50 μm). C/D. Quantification of ciliated cells (C) and secretory cells (D) of the organoids from WT mice and dKO mice across different culture time. ①P=0.004, ②P=0.005, ③P=0.001, ④P=0.000, compared with the WT group.

Fig 5 Cell composition of the oviductal epithelial organoids