CXCL9在乳腺癌中的表达及其与肿瘤免疫浸润特征的相关性研究

杜少倩, 陶梦玉, 曹源, 王红霞, 胡孝渠, 范广建, 臧丽娟

CXCL9 expression in breast cancer and its correlation with the characteristics of tumor immunoinfiltration

DU Shaoqian, TAO Mengyu, CAO Yuan, WANG Hongxia, HU Xiaoqu, FAN Guangjian, ZANG Lijuan

图5 CXCL9的PPI网络构建和 CXCL9 及其相关基因的GO功能分析和KEGG通路分析 Note： A. PPI network of CXCL9. Red indicates proteins with CXCL9 interaction score >0.9, and blue indicates proteins with CXCL9 interaction score >0.7. PF4—platelet factor 4; PF4V1—platelet factor 4 variant 1; MAP2K3/6—dual specificity mitogen-activated protein kinase kinase 3/6; GNAI2—guanine nucleotide-binding protein G(i) subunit alpha-2; GNG2—guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2; GNB1—guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; SFTPC—surfactant protein C; CCR1—C-C chemokine receptor type 1; CXCR1—C-X-C chemokine receptor type 1; CX3CR1—CX3C chemokine receptor 1; CCL5—C-C motif chemokine ligand 5; DPP4—dipeptidyl peptidase-4; GPR29—chemokine (C-C motif) receptor 6; XCR1—chemokine XC receptor 1; C1QA/B—complement component 1, Q subcomponent, A chain/B chain; IDO1—indoleamine 2,3-dioxygenase 1; SLAMF8—SLAM family member 8; ADAMDEC1—adam-like, decysin 1; GBP5—guanylate-binding protein 5. B/C. GO function analysis (B) and KEGG pathway analysis (C) of CXCL9 and its related genes.

Fig 5 PPI network construction of CXCL9 and GO functional analysis and KEGG pathway analysis of CXCL9 and its related genes