SIRT2通过组蛋白H4K8去乳酸化修饰调控巨噬细胞趋化功能

宋文汀, 陶悦, 潘艺, 莫茜, 曹清

SIRT2 regulates macrophage chemotaxis by de-modifying histone H4K8 lactylation

SONG Wenting, TAO Yue, PAN Yi, MO Xi, CAO Qing

图2 蛋白质印迹法检测巨噬细胞组蛋白修饰水平 Note： A. Detection of histone lactylation (left) and acetylation (right) levels by Western blotting. B. Expression of histone lactylation (above) and acetylation (below). ①P=0.000,②P=0.002, compared with the CTRL group.

Fig 2 Histone modification levels in macrophages detected by Western blotting