SIRT2通过组蛋白H4K8去乳酸化修饰调控巨噬细胞趋化功能

宋文汀, 陶悦, 潘艺, 莫茜, 曹清

SIRT2 regulates macrophage chemotaxis by de-modifying histone H4K8 lactylation

SONG Wenting, TAO Yue, PAN Yi, MO Xi, CAO Qing

图3 LPS处理后巨噬细胞Sirtuin家族和 HDAC 家族的RNA表达水平 Note： A. Expression of Sirtuin family mRNA. B. Expression of HDAC family mRNA. C. Detection of SIRT2 protein by Western blotting. ①P=0.010, compared with the CTRL group.

Fig 3 RNA expression levels of Sirtuin family and HDAC family of macrophages after LPS treatment