转位分子蛋白经由Keap1/Nrf2/HO-1通路激活自噬缓解大鼠糖尿病神经病理性疼痛

高楠, 郝璨, 马冰洁, 靳天, 马柯, 刘晓明

Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling

GAO Nan, HAO Gem, MA Bingjie, JIN Tian, MA Ke, LIU Xiaoming

图1 2型糖尿病大鼠并发神经病理性疼痛 (n=6) Note：A/B. The levels of HOMA-IR (A) and ISI (B) of the Sham group and the DNP group 3 d after STZ injection. C. 50% PMWT of the Sham group and the DNP group 3 d after STZ injection. ①P=0.000, compared with the Sham group.

Fig 1 T2DM rats showed pain hypersensitivity (n=6)