转位分子蛋白经由Keap1/Nrf2/HO-1通路激活自噬缓解大鼠糖尿病神经病理性疼痛

高楠, 郝璨, 马冰洁, 靳天, 马柯, 刘晓明

Translocator protein activates autophagy in diabetic neuropathic pain rats via regulation of the Keap1/Nrf2/HO-1 signaling

GAO Nan, HAO Gem, MA Bingjie, JIN Tian, MA Ke, LIU Xiaoming

图2 鞘内注射TSPO激动剂Ro5-4864对DNP大鼠50% PMWT的影响 (n=6) Note：①P=0.000, compared with the Sham group; ②P=0.039, ③P=0.000, compared with the DNP group.

Fig 2 Effects of TSPO agonist Ro5-4864 on the 50% PMWT in DNP rats (n=6)