Metabolites of gut microbial-proteins, peptides and amino acids/gut microbial-host co-metabolism | Catechol | Lactobacillus[+ -] Clostridium[] | | | | | | | 1.09 | -1.06 | 1.42① |
Phenylpropionic acid | 1.01 | 1.75① | 1.48① | 5.27① | 8.35① | 5.44① | | | |
2-hydroxyphenylpropionic acid | | | | | | | -2.08① | -2.33① | -2.33① |
L-DOPA | | | | | | | 1.10 | -1.44① | -1.30① |
Phenylalanine | 1.12 | 1.20① | 1.23① | | | | -1.28 | -1.43① | -1.49① |
Tyrosine | 1.41① | 1.53① | 1.58① | | | | | | |
4-aminobutyric acid | Clostridium[] | | | | | | | -1.30 | -1.79① | -1.35 |
Ornithine | 1.21① | 1.31① | 2.03① | | | | -2.08① | -1.85① | -2.00① |
Spermidine | | | | | | | 1.58① | 2.17① | 2.30① |
Tryptophan | Escherichia coli[+ -] Bifidobacterium[+] | 1.07 | 1.41① | 1.46① | | | | | | |
Indole-3-acetic acid | | | | | | | 1.12 | 2.06① | 1.92① |
Indole-3-propionic acid | | | | | | | 1.00 | -1.10 | -2.00① |
Indole-3-lactic acid | 1.08 | 1.36① | 1.43① | | | | | | |
Kynurenic acid | | | | 1.29① | 1.44① | -7.14① | | | |
Xanthuric acid | | | | | | | -1.09 | -1.25① | -1.47① |
Nicotinic acid | | | | -1.11 | -1.11 | 2.85① | -1.12 | -1.25① | -1.28① |
Deoxycholic acid | Lactobacillus[+ -] Bifidobacterium[+] Bacteroides[+] Escherichia coli[+ -] Clostridium[] | | | | -1.03 | 1.04 | 2.88① | | | |
Cholesterol | 1.75① | 1.84① | 2.46① | -1.85 | -4.17① | -3.85① | | | |
Isoleucine | | 1.18 | 1.18 | 1.22① | | | | -1.26 | -1.28① | -1.39① |
Leucine | 1.15 | 1.19 | 1.24① | | | | -1.17 | -1.25① | -1.26① |
Valine | 1.21 | 1.19 | 1.26① | | | | -1.21 | -1.58① | -1.67① |
Isovaleric acid | | | | | 1.28 | 1.02 | -2.94① | | | |
Caproic acid | | | | 1.04 | 4.37① | 4.30① | | | |
TCA cycle | Fumaric acid | Bifidobacterium[+] Lactobacillus[+ -] | 2.29① | 2.84① | 3.83① | 1.73① | 1.28 | 1.25① | -1.85① | -1.79① | -1.75① |
Malic acid | 1.60① | 2.28① | 3.49① | 1.71① | -1.06① | 1.00 | -1.64① | -2.17① | -2.04① |
α-ketoglutaric acid | 1.33 | 1.34 | 1.60① | | | | | | |
Citric acid | 1.48① | 1.41① | 1.74① | | | | | | |
Isocitrate | 1.53 | 1.64① | 1.77① | | | | | | |
TCA cycle-amino acid | Glutamic acid | | 1.27① | 1.31① | 1.43① | | | | -1.23 | -1.61① | -1.72① |
Glutamine | 2.15① | 2.37① | 3.08① | | | | | | |
Aspartic acid | 1.31① | 1.46① | 1.60① | | | | | | |
Asparagine | 1.17 | 1.59① | 1.40① | | | | | | |
TCA cycle-glycometabolism | Pyruvate | Bifidobacterium[+] Bacteroides[+] Lactobacillus[+ -] | 1.09 | 1.37 | 1.67① | -1.03 | 1.47 | 2.48① | | | |
Lactic acid | 1.16 | 1.46① | 1.46① | 1.55① | -1.07 | -1.05 | -3.52① | -2.68① | -1.05① |
Fructose | 1.08 | 1.23① | 1.41① | 1.46① | 2.20① | 3.41① | | | |
6-phosphogluconic acid | -1.09① | -1.10① | -1.33① | 1.34① | 1.55① | -10.00① | | | |
D-glycero-1-phosphate | 1.45 | 1.95① | 2.03① | -1.35① | -1.37 | -1.69① | | | |
Glucose-1-phosphate | 1.05 | 0.85 | 1.42① | 1.31 | 1.22 | -2.63① | -1.25① | -1.29① | -1.31① |
β-glycerophosphate | | | | -1.33① | 1.00 | -1.56① | | | |
Ethanolamine phosphate | | | | 1.21 | -1.67 | -1.96① | | | |
Phosphoenolpyruvate | | | | 1.54① | 1.32 | -1.56① | | | |
TCA cycle-lipid metabolism | Linolenic acid | Bifidobacterium[+] Lactobacillus[+-] | | | | | | | 1.04 | -1.53① | -1.52① |
Docosanoic acid | 1.32 | 3.29① | 1.92① | | | | | | |
13-docosenoic acid | 1.43 | 1.80① | 2.27① | | | | | | |
1-monostearoylglycerol | -1.30 | 1.01 | 1.53① | | | | | | |