BRCA1 R1325K突变对胆囊癌细胞增殖及凋亡的影响

杨婧潇, 贾子尧, 吴文广, 吴向嵩, 张飞, 李怀峰, 朱逸荻, 李茂岚

Effect of BRCA1 R1325K mutation on proliferation and apoptosis of gallbladder cancer cells

YANG Jingxiao, JIA Ziyao, WU Wenguang, WU Xiangsong, ZHANG Fei, LI Huaifeng, ZHU Yidi, LI Maolan

图5 BRCA1 R1325K突变对胆囊癌细胞系GBC-SD和NOZ凋亡相关蛋白表达情况的影响 Note： A. Effects of BRCA1 R1325K mutation on expression of apoptosis-related proteins in GBC-SD cell line. B. Effects of BRCA1 R1325K mutation on expression of apoptosis-related proteins in NOZ cell line. cPARP—cleaved PARP. ①P=0.000, ②P=0.004, ③P=0.002, ④P=0.009.

Fig 5 Effects of BRCA1 R1325K mutation on expression of apoptosis-related proteins in gallbladder cancer cell lines GBC-SD and NOZ