间歇性禁食联合产热脂肪活化防治小鼠肥胖作用研究

吴凯敏, 麻静, 赵旭赟

Combined effects of intermittent fasting and thermogenic fat activation on the treatment and prevention of obesity in mice

WU Kaimin, MA Jing, ZHAO Xuyun

图9 间歇性禁食联合产热脂肪活化对高脂饮食小鼠白色脂肪组织代谢的影响 Note： A. The expression of thermogenic genes in the eWAT analyzed by RT-qPCR. B. The expression of fatty acid oxidation genes in the eWAT analyzed by RT-qPCR. C. The expression of thermogenic genes in the iWAT analyzed by RT-qPCR. D. The expression of fatty acid oxidation genes in the iWAT analyzed by RT-qPCR. ①P=0.000, ④P=0.003, ⑥P=0.019, ⑦P=0.001, ⑧P=0.002, ⑨P=0.006, ?P=0.004, ?P=0.014, ?P=0.008, ?P=0.007, ?P=0.029, ?P=0.021, ?P=0.024, 21P=0.023, 22P=0.042, compared with the Ctrl2 group; ②P=0.001, ⑤P=0.000, ⑩P=0.006, ?P=0.020, ?P=0.041, ?P=0.005, 23P=0.010, 24P=0.003, compared with the IF2 group; ③P=0.012, compared with the CL2 group.

Fig 9 Effect of intermittent fasting combined with thermogenic fat activation on metabolism of white fat tissues in mice on a high-fat diet