大腿骨骼肌肌内脂肪组织的含量对肥胖症男性患者糖代谢的影响

卢晓冰, 岳江, 何晟赟, 董莹, 路青, 麻静

Effect of intramuscular adipose tissue in the skeletal muscle of thigh on glucose metabolism in male patients with obesity

LU Xiaobing, YUE Jiang, HE Shengyun, DONG Ying, LU Qing, MA Jing

表1 2组患者的一般资料和实验室检测指标比较

Tab 1 Comparation of general data and laboratory test indicators of obese patients between the two groups

Item NGT group (n=41) IGR group (n=39) P value General data Age/year 32.00 (28.50, 42.00) 35.00 (31.00, 41.00) 0.338 BMI/(kg·m-2) 34.34 (30.80, 38.55) 34.56 (31.95, 37.65) 0.605 WC/cm 114.31±11.55 124.25±18.26 0.017 HC/cm 115.00 (107.00, 122.00) 117.50 (110.25, 126.25) 0.101 WHR 0.99±0.06 1.01±0.06 0.095 Laboratory test indicators FBG/(mmol·L-1) 5.10 (4.63, 5.43) 5.99 (5.33, 7.54) 0.000 PBG-0.5h/(mmol·L-1) 8.61 (7.56, 9.92) 9.24 (8.32, 11.41) 0.043 PBG-1h/(mmol·L-1) 9.18 (6.97, 9.97) 12.39 (9.87, 13.99) 0.000 PBG-2h/(mmol·L-1) 6.41 (5.78, 7.03) 10.35 (8.88, 12.86) 0.000 PBG-3h/(mmol·L-1) 4.18 (3.78, 4.81) 6.60 (5.71, 8.81) 0.000 FINS/(μIU·mL-1) 15.12 (10.15, 20.69) 21.20 (12.02, 28.63) 0.064 INS-0.5h/(μIU·mL-1) 107.18 (80.63, 162.12) 79.47 (25.74, 116.61) 0.025 INS-1h/(μIU·mL-1) 127.05 (83.54, 171.24) 113.44 (52.24, 175.94) 0.307 INS-2h/(μIU·mL-1) 70.69 (45.45, 117.95) 98.84 (53.35, 205.92) 0.028 INS-3h/(μIU·mL-1) 20.75 (11.08, 28.14) 48.82 (33.61, 106.97) 0.000 FCP/(ng·mL-1) 3.95 (3.33, 4.85) 4.67 (3.80, 5.73) 0.037 CP-0.5h/(ng·mL-1) 11.83 (8.13, 13.76) 7.96 (6.41, 12.01) 0.015 CP-1h/(ng·mL-1) 13.22 (10.83, 16.94) 10.77 (8.43, 16.27) 0.115 CP-2h/(ng·mL-1) 11.43 (9.17, 14.97) 13.68 (10.87, 18.24) 0.051 CP-3h/(ng·mL-1) 6.01 (4.43, 7.84) 10.29 (8.03, 12.70) 0.000 HbA1c/% 5.50 (5.20, 5.70) 6.45 (5.70, 7.95) 0.000 HOMA-IR 3.31 (2.14, 4.56) 6.24 (3.45, 8.17) 0.002 GPT/(U·L-1) 40.00 (20.00, 69.00) 67.00 (38.00, 87.00) 0.013 GOT/(U·L-1) 22.00 (16.00, 35.75) 36.00 (25.00, 54.00) 0.001 GGT/(U·L-1) 40.50 (26.00, 55.00) 52.00 (41.00, 77.00) 0.002 BUN/(mmol·L-1) 4.83±1.08 4.60±0.99 0.324 Cre/(μmol·L-1) 79.97±12.98 74.28±13.37 0.060 UA/(mmol·L-1) 487.82±122.65 479.23±104.40 0.740 TAG/(mmol·L-1) 1.63 (1.25, 2.71) 2.36 (1.83, 3.41) 0.010 TC/(mmol·L-1) 5.01±1.09 5.44±0.99 0.068 HDL-C/(mmol·L-1) 1.09±0.24 1.06±0.20 0.531 LDL-C/(mmol·L-1) 3.07±0.84 3.34±0.86 0.164 NEFA/(mmol·L-1) 0.53 (0.47, 0.64) 0.69 (0.57, 0.78) 0.004