肝细胞癌相关的核编码线粒体基因及临床信息的综合预后模型

克德尔亚·艾山江, 傅怡, 赖冬林, 邬海龙, 龚伟

An integrated prognostic model of nuclear-encoded mitochondrial gene signature and clinical information for hepatocellular carcinoma

Aishanjiang Kedeerya, FU Yi, LAI Donglin, WU Hailong, GONG Wei

图1 预后相关NEMG的识别和基于6-NEMG的风险特征模型的构建 Note： A. DEGs between HCC and adjacent paired normal tissues. Red dots represent significant upregulation and blue dots represent significant downregulation of DEGs in HCC tissues. B. Heatmap of 264 deNEMGs in TCGA cohort. N—adjacent paired normal tissues; T—HCC tumor tissues. C. Venn diagram showing differently expressed deNEMGs between tumor and adjacent tissues. D. Univariate Cox regression analysis of 6 significant prognostic NEMGs associated with OXPHOS, TCA cycle and cell apoptosis. E. Multivariate Cox analysis of 6-NEMG risk signature.

Fig 1 Identification of prognosis-related NEMGs and construction of a 6-NEMG-based risk signature