黄芪对甲状腺功能正常的桥本甲状腺炎患者外周血T淋巴细胞亚群表达的影响

李自云, 庄新娟, 季业, 田海荣, 殷峻

Effects of Astragali Radix on T lymphocyte subsets expression in peripheral blood of Hashimoto′s thyroiditis patients with normal thyroid function

LI Ziyun, ZHUANG Xinjuan, JI Ye, TIAN Hairong, YIN Jun

表1 2组患者治疗前后基本资料的比较

Tab 1 Comparison of general information before and after treatment in the two groups

Index Before treatment (n=59) After treatment (n=59) Intervention group Control group P value Intervention group Control group P value Male/female/n 3/56 4/55 0.726 Age/year 46±13 44±15 0.852 Duration of HT/month 23 (7, 31) 26 (8, 34) 0.607 29 (13, 37) 32 (14, 40) 0.607 Smoke/[n(%)] 0 (0) 0 (0) 1.000 0 (0) 0 (0) 1.000 Drink/[n(%)] 0 (0) 0 (0) 1.000 0 (0) 0 (0) 1.000 BMI/(kg·m-2) 22.4±3.5 23.2±3.1 0.624 22.7±3.6 23.5±3.4 0.655 Scr/(μmol·L-1) 61.2±15.4 59.1±16.1 0.682 60.4±14.8 60.7±17.5 0.832 eGFR/(mL·min-1·1.73-1·m-2) 117.1±24.3 120.4±25.1 0.734 114.7±23.5 117.8±23.3 0.855 GPT/(U·L-1) 24±12 23±10 0.567 23±11 24±10 0.786 AST/(U·L-1) 21 (16, 31) 23 (14, 29) 0.301 20 (12, 28) 24 (14, 43) 0.243 γ-GT/(U·L-1) 32.5 (17.5, 41.0) 35.3 (18.1, 43.4) 0.661 31.2 (15.7, 42.2) 37.9 (19.0, 45.6) 0.318 TC/(mmol·L-1) 5.12±1.34 4.96±1.60 0.620 4.84±1.40 4.91±1.28 0.701 TAG/(U·L-1) 2.56 (1.26, 4.07) 2.69 (1.42, 3.93) 0.734 2.47 (1.16, 4.22) 2.78 (1.67, 4.33) 0.796 MUI/(μg·L-1) 145 (106, 187) 149 (110, 190) 0.864 128 (95, 171) 135 (108, 178) 0.764 Thyroid gland/cm3 25.53 (18.79, 28.35) 24.35 (17.02, 26.23) 0.805 23.47 (17.43, 26.18) 23.05 (16.53, 25.62) 0.909