黄芪对甲状腺功能正常的桥本甲状腺炎患者外周血T淋巴细胞亚群表达的影响

李自云, 庄新娟, 季业, 田海荣, 殷峻

Effects of Astragali Radix on T lymphocyte subsets expression in peripheral blood of Hashimoto′s thyroiditis patients with normal thyroid function

LI Ziyun, ZHUANG Xinjuan, JI Ye, TIAN Hairong, YIN Jun

表3 2组患者T淋巴细胞亚群及炎症因子治疗前后比较

Tab 3 Comparison of T lymphocyte subsets and cellular inflammatory factors before and after treatment in the two groups

Index Intervention group (n=59) Control group (n=59) Before treatment After treatment Before treatment After treatment CD3+/% 59.23±4.12 68.14±4.52 57.15±5.38 60.45±5.70 CD4+/% 34.36±5.54 44.56±4.26①⑤ 32.17±5.16 34.11±5.06 CD8+/% 22.20±4.23 21.12±4.01 22.48±3.35 22.15±2.26 CD4+/CD8+ 1.55 (1.10, 2.03) 2.11 (1.63, 2.82)①⑤ 1.43 (1.13, 1.92) 1.54 (1.21, 1.91) IL-2/(pg·mL-1) 4.27 (2.23, 9.27) 2.99 (2.01, 6.48)②⑥ 4.20 (2.00, 8.99) 4.13 (2.01, 8.78) TNF-α/(pg·mL-1) 8.92 (3.59, 17.47) 7.71 (3.25, 15.42)③⑥ 8.71 (4.05, 17.69) 8.59 (3.32, 17.43) IL-6/(pg·mL-1) 3.74 (1.05, 7.99) 5.04 (2.25, 11.45)④⑦ 3.45 (1.34, 8.11) 3.50 (1.15, 8.03) IL-10/(pg·mL-1) 7.08 (3.05, 17.14) 8.71 (4.11, 18.09)②⑧ 7.17 (3.43, 17.01) 7.03 (3.21, 16.31) hs-CRP/(mg·L-1) 6.46 (1.55, 8.78) 3.27 (0.76, 5.16)①⑤ 6.76 (1.78, 9.68) 6.37 (1.97, 9.77) ESR//(mg·L-1) 15.5 (8.4, 23.0) 12.6 (8.3, 19.5)④⑨ 14.9 (8.9, 22.6) 14.1 (9.1, 21.4)