甲状腺弥漫性大B细胞淋巴瘤临床病理特征、基因突变谱及预后分析
Clinicopathologic characteristics, gene mutation profile and prognostic analysis of thyroid diffuse large B-cell lymphoma
Note： TET2—tet methylcytosine dioxygenase 2; KMT2D—lysine methyltransferase 2D; TP53—tumor protein p53; GNA13—G protein subunit α13; KMT2C—lysine methyltransferase 2C; BTG2—BTG anti-proliferation factor 2; FOXO1—forkhead box O1; SGK1—serum/glucocorticoid regulated kinase 1; SOCS1—suppressor of cytokine signaling 1; TNFRSF14—TNF receptor superfamily member 14; ATM—ATM serine/threonine kinase; CCND3—cyclin D3; EBF1—EBF transcription factor 1; EZH2—enhancer of zeste 2 polycomb repressive complex 2 subunit; PIM1—Pim-1 proto-oncogene, serine/threonine kinase; B2M—β2-microglobulin; CREBBP—CREB binding protein; DDX3X—DEAD-box helicase 3 X-linked; DTX1—deltex E3 ubiquitin ligase 1; MYD88—MYD88 innate immune signal transduction adaptor; ARID1A—AT-rich interaction domain 1A; BTG1—BTG anti-proliferation factor 1; CARD11—caspase recruitment domain family member 11; CD70—CD70 molecule; DUSP2—dual specificity phosphatase 2; HIST1H1E—H1.4 linker histone, cluster member; MYC—MYC proto-oncogene, bHLH transcription factor; NFKBIE—NFKB inhibitor epsilon; TMSB4X—thymosin β4 X-linked; ZFP36L1—ZFP36 ring finger protein-like 1; ZNF608—zinc finger protein 608; BCL6—BCL6 transcription repressor; CD58—CD58 molecule; NOTCH1—notch receptor 1; PTPN6—protein tyrosine phosphatase non-receptor type 6; TBL1XR1—TBL1X/Y-related 1; TNFAIP3—TNFα-induced protein 3; TSC2—TSC complex subunit 2; CIITA—class Ⅱ major histocompatibility complex transactivator; EP300—E1A binding protein p300; FAS—Fas cell surface death receptor; IRF4—interferon regulatory factor 4; IRF8—interferon regulatory factor 8; mTOR—mechanistic target of rapamycin kinase; STAT3—signal transducer and activator of transcription 3; FBXW7—F-box and WD repeat domain containing 7; HIST1H1C—H1.2 linker histone, cluster member; LYN—LYN proto-oncogene, Src family tyrosine kinase; MAPK7—mitogen-activated protein kinase 7; MPEG1—macrophage-expressed 1; STAT6—signal transducer and activator of transcription 6.
