超重肥胖青少年认知功能的改变及其与血清FGF21水平的关系

韩瑞, 吴倩, 刘丹, 程棣, 张盈, 倪嘉成, 康飘, 陈安然, 于淑洁, 方启晨, 李华婷

Alteration of cognitive function in overweight and obese adolescents and its relationship with serum FGF21 levels

HAN Rui, WU Qian, LIU Dan, CHENG Di, ZHANG Ying, NI Jiacheng, KANG Piao, CHEN Anran, YU Shujie, FANG Qichen, LI Huating

表2 3组受试者的认知功能评估

Tab 2 Cognitive function assessment of the three groups of subjects

Item Normal weight group (n=50) Overweight group (n=50) Obese group (n=75) P value Flanker task ACC Congruent stimulus 0.97 ± 0.09 0.97 ± 0.04 0.98 ± 0.04 0.442 Incongruent stimulus 0.92 ± 0.09 0.93 ± 0.10 0.92 ± 0.14 0.854 Reaction time/ms Congruent stimulus 406.12 ± 108.32 431.35 ± 85.17 475.13 ± 84.31 0.000 Incongruent stimulus 465.41 ± 95.59 463.55 ± 59.92 524.01 ± 103.79 0.000 n-back task ACC 0-back 0.94 ± 0.05 0.93 ± 0.07 0.93 ± 0.08 0.641 1-back 0.84 ± 0.12 0.85 ± 0.08 0.86 ± 0.12 0.404 2-back 0.78 ± 0.13 0.72 ± 0.16 0.78 ± 0.15 0.751 Reaction time/ms 0-back 522.52 ± 103.11 539.48 ± 104.85 564.34 ± 116.74 0.050 1-back 541.76 ± 149.67 587.90 ± 160.04 656.60 ± 168.99 0.000 2-back 570.49 ± 174.48 625.08 ± 199.08 754.24 ± 201.57 0.000