基于临床检验指标建立肺腺癌患者浸润程度判别模型

王梦菲, 杨守志, 乔永霞, 黄琳

Establishment of discriminative models for predicting the infiltration degree of patients with lung adenocarcinoma based on clinical laboratory indicators

WANG Mengfei, YANG Shouzhi, QIAO Yongxia, HUANG Lin

表2 2组患者的检验指标单因素分析

Tab 2 Single factor analysis of test indicators between the two groups

Item Pre-invasive lesion Invasive lesion Ｚ/χ2/ t value P value Tumor marker Count/n 59 143 N/A N/A CEA/(ng·mL-1) 1.45 (1.11, 1.86) 2.32 (1.78, 3.34) -3.09 0.002 CYFRA21-1/(ng·mL-1) 2.01 (1.56, 2.58) 2.09 (1.62, 2.87) -1.027 0.304 SCC/(ng·mL-1) 0.41 (0.29, 0.52) 0.43 (0.32, 0.62) -1.344 0.179 NSE/(ng·mL-1) 16.32±4.43 15.84±5.15 0.626 0.532 CA125/(U·mL-1) 10.9 (7.09, 13.07) 10.66 (7.36, 15.4) -0.754 0.451 proGRP/(pg·mL-1) 47.52 (37.93) 47.52 (38.71, 55.85) -0.046 0.963 Coagulation function indicator Count/n 49 119 N/A N/A FBG/(g·L-1) 2.58 (2.35, 3.14) 2.98 (2.58, 3.53) -2.725 0.006 Blood routine indicator Count/n 58 138 N/A N/A MCV/fL 90.05 (87, 92.38) 91.35 (89.2, 93.83) -2.108 0.035 MCH/(g·L-1) 30.55 (29.35, 31.33) 31.1 (30, 31.8) -2.218 0.027 BASO%/% 0.25 (0.1, 0.43) 0.3 (0.2, 0.5) -2.12 0.034 EO%/% 0.7 (0.1, 1.43) 1.2 (0.48, 2.03) -2.256 0.024 EO#/(109·L-1) 0 (0, 0.1) 0.1 (0, 0.1) -2.047 0.041 Biochemical indicator Count/n 58 142 N/A N/A Urea/(mmol·L-1) 4.6 (4.18, 5.93) 5.2 (4.3, 6.3) -2.242 0.025 PAB/(g·L-1) 0.28 (0.24, 0.31) 0.26 (0.24, 0.29) -2.415 0.016 RBP/(mg·L-1) 44.5 (39.75, 51.25) 42 (38, 46) -2.274 0.023 ALB/(g·dL-1) 4.62 (4.36, 4.82) 4.48 (4.32, 4.68) -2.316 0.021 TBA/(μmol·L-1) 3.5 (2, 5) 4 (2, 6) -2.061 0.039