癌-睾丸抗原CT63在慢性髓系白血病中的作用及其机制

孔汝心, 周亚群, 魏婷宜, 雷鸣

Function and mechanism of cancer-testis antigen CT63 in chronic myeloid leukemia

KONG Ruxin, ZHOU Yaqun, WEI Tingyi, LEI Ming

图2 CT63 敲降后K562细胞在裸鼠皮下成瘤的能力变化 Note： A. Subcutaneous tumor of nude mice. B. Average radiant efficiency of region of interest. C. Tumor size. D. Tumor weight. E. H-E staining of tumor. F/H. Immunofluorescence staining of CT63 and Ki67 in tumor tissue. G/I. Relative fluorescence density of Immunofluorescence staining in F and H. ①P=0.000, ②P=0.029, ③P=0.000, ④P=0.000, compared with the shCtrl group.

Fig 2 Tumorigenic ability of K562 cells in nude mice after down-regulation of CT63