双同源盒诱导小鼠胚胎干细胞向胚外内胚层分化的机制研究

洪磊, 郭传亮, 蔡勤, 李婉睿, 曾溢滔, 薛燕, 曾凡一

Mechanism of DUX-induced differentiation of mESC into extraembryonic endoderm

HONG Lei, GUO Chuanliang, CAI Qin, LI Wanrui, ZENG Yitao, XUE Yan, ZENG Fanyi

图1 2CLC的鉴定 Note： A. Microscopy pictures and flow cytometry showing the percentage of 2CLCs. B. RT-qPCR validation of selected 2C marker genes and MERVL-polymerase gene (MERVL-pol) in noDox (control) and plusDox (DUX overexpression) ES cells. ①P<0.001, compared with the control group.

Fig 1 Identification of 2CLCs