双同源盒诱导小鼠胚胎干细胞向胚外内胚层分化的机制研究

洪磊, 郭传亮, 蔡勤, 李婉睿, 曾溢滔, 薛燕, 曾凡一

Mechanism of DUX-induced differentiation of mESC into extraembryonic endoderm

HONG Lei, GUO Chuanliang, CAI Qin, LI Wanrui, ZENG Yitao, XUE Yan, ZENG Fanyi

图4 DUX调控ESC分化潜能的可能机制 Note： A. Intersection of DUX-upregulated genes with RARG and DUX co-localized genes and possible mechanism of regulating mESCs. B. IGV view of RNA-seq and ChIP-seq results. C. KEGG analysis of the intersecting genes.

Fig 4 Potential mechanism of DUX regulation on ESCs differentiation