MTA1在子痫前期胎盘组织中的表达及其对滋养细胞功能的影响

耿瑶, 张杨, 赵洁, 李伟, 蔡国青

Expression of MTA1 in preeclamptic placental tissue and its effects on trophoblast function

GENG Yao, ZHANG Yang, ZHAO Jie, LI Wei, CAI Guoqing

图2 敲低 MTA1 对HTR8/SVneo细胞功能的影响 Note： A. Expression of MTA1 protein in HTR8/SVneo cells with stable MTA1 knockdown by Western blotting. B. Wound healing assay. Representative images were taken at the beginning of wound healing (0 h) and 24 h later. The level of cell migration towards the wound scratches was quantified by measuring the distance of wound closure. C. Invasive capacity of the cells by Transwell in vitro invasion assay and statistical analysis. D. Expression levels of MMP-2 and MMP-9 by qRT-PCR. n=4. ①P=0.002, ②P=0.015, ③P=0.020, ④P=0.003.

Fig 2 Impact of MTA1 knockdown on the functional properties of HTR8/SVneo cells