基于生理药物代谢动力学模型预测氯氮平联合用药的药物相互作用
Prediction of drug-drug interactions in clozapine combination therapy based on physiologically based pharmacokinetic model
基于生理药物代谢动力学模型预测氯氮平联合用药的药物相互作用 |
| 牟凡, 黄志伟, 程渝, 赵雪, 李华芳, 禹顺英 |
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Prediction of drug-drug interactions in clozapine combination therapy based on physiologically based pharmacokinetic model |
| MOU Fan, HUANG Zhiwei, CHENG Yu, ZHAO Xue, LI Huafang, YU Shunying |
| 图5 剂量优化前后氯氮平的药时曲线比较 |
| Fig 5 Comparison of plasma concentration-time curve profiles of clozapine before and after dose optimization |
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