长寿蛋白SIRT6在衰老和代谢中作用的研究进展

刘永慧, 唐莉, 梁泰刚, 张健, 冯丽

Research progress in the role of SIRT6 in aging and metabolism

LIU Yonghui, TANG Li, LIANG Taigang, ZHANG Jian, FENG Li

图1 人源SIRT6蛋白的二级结构 Note： The structural composition of SIRT6 is basically divided into Rossmann fold structure, small structural domains (including the zinc finger module), C-terminal extension (CTE) and N-terminal extension (NTE). SIRT6 is shown as a purple cartoon structure with lake blue stick structures for NAD+ and green for ADP ribose.

Fig 1 Secondary structure of the human protein SIRT6