长寿蛋白SIRT6在衰老和代谢中作用的研究进展

刘永慧, 唐莉, 梁泰刚, 张健, 冯丽

Research progress in the role of SIRT6 in aging and metabolism

LIU Yonghui, TANG Li, LIANG Taigang, ZHANG Jian, FENG Li

图3 SIRT6 激动剂的化学结构和结合模式 Note： A. Chemical structures of SIRT6 agonist, MDL-800, MDL-801, and UBCS039. B. The binding modes of MDL-801 or UBCS039 with SIRT6. MDL-801 and UBCS039 are shown in green and blue sticks, respectively.

Fig 3 Structure and binding modes of SIRT6 activators