血管抑制蛋白2在三阴性乳腺癌中的功能及其调控可变剪接机制

王卫, 王红丽, 阿力比亚提·艾尼, 衣力亚尔·肉苏, 阿依努尔, 杨亮

Function of vasohibin-2 and the mechanism of alternative splicing in triple-negative breast cancer

WANG Wei, WANG Hongli, ALIBIYATI·i Ain, YILIYAER· Rousu, AYI NUER, YANG Liang

图6 富含细胞凋亡事件的可变剪接基因 Note： A. Wayne diagram of the gene set with significantly altered AS expression levels in the cell cycle and p53 signaling pathway. B. ASE of the VASH2-regulated gene TSC2 and IGV-sashimi plot showing A3SS & ES events. C.ASE of the VASH2-regulated gene SMAD2 and IGV-sashimi plot showing ES events. D. ASE of the VASH2-regulated gene CASP8. ①P=0.006, ②P=0.017, ③P=0.027.

Fig 6 Apoptosis-enriched alternative splicing genes