基于单细胞测序技术解析冠状动脉粥样硬化患者平滑肌细胞的细胞间通信及关键基因

司春婴, 王建茹, 李晓辉, 王永霞, 关怀敏

Study on intercellular communication and key genes of smooth muscle cells in human coronary atherosclerosis based on single cell sequencing technology

SI Chunying, WANG Jianru, LI Xiaohui, WANG Yongxia, GUAN Huaimin

图6 关键基因介导的细胞间通信 Note： A. Cellular communication network diagram mediated by CCL signaling pathway. B. Heat map of cell action types in the CCL signaling pathway. C. Bar chart of the contribution of L-R in the CCL signaling pathway. D. CCL2-ACKR1-mediated cellular communication network diagram. E. Cellular communication network diagram mediated by complement signaling pathway. F. Heat map of cellular action types in complement signaling pathways. G. Bar graph of the contribution of L-R in the complement signaling pathway. H. C3-(ITGAM+ITGB2)-mediated cellular communication network diagram. I. C3-(ITGAX+ITGB2)-mediated cellular communication network diagram.

Fig 6 Hub genes-mediated cellular communication