甲基莲心碱调节SDF-1/CXCR4信号通路对糖尿病肾病的影响

王莹, 平立风, 刘彤彤, 刘珊珊, 刘磊

Effect of neferine on diabetic nephropathy by regulating SDF-1/CXCR4 signal pathway

WANG Ying, PING Lifeng, LIU Tongtong, LIU Shanshan, LIU Lei

图6 各组大鼠肾组织中 Sdf-1 、 Cxcr4 mRNA表达比较 Note： A. Relative expression of Sdf-1 mRNA. B. Relative expression of Cxcr4 mRNA. ①P=0.000, compared with the normal group; ②P=0.000, compared with the DN group; ③P=0.000, compared with the Nef low-dose group; ④P=0.000, compared with the Nef medium-dose group; ⑤P=0.000, compared with the Nef high-dose group.

Fig 6 Comparison of Sdf-1 and Cxcr4 mRNA expression in renal tissues of rats in each group