甲基莲心碱调节SDF-1/CXCR4信号通路对糖尿病肾病的影响

王莹, 平立风, 刘彤彤, 刘珊珊, 刘磊

Effect of neferine on diabetic nephropathy by regulating SDF-1/CXCR4 signal pathway

WANG Ying, PING Lifeng, LIU Tongtong, LIU Shanshan, LIU Lei

图7 各组大鼠肾组织中SDF-1、CXCR4蛋白表达 Note： A. Western blotting analysis of SDF-1 and CXCR4 protein expression. B/C. Statistical analysis of relative expression of SDF-1 protein (B) and CXCR4 protein (C). ①P=0.000, compared with the normal group; ②P=0.000, compared with the DN group; ③P=0.000, compared with the Nef low-dose group; ④P=0.000, compared with the Nef medium-dose group; ⑤P=0.000, compared with the Nef high-dose group.

Fig 7 SDF-1 and CXCR4 protein expression in renal tissues of rats in each group