基于实验室指标的系统性红斑狼疮鉴别诊断列线图的构建及评估
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杨婧偊, 陈留宝, 王康太, 杨兴智, 于海涛
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Establishment and evaluation of nomogram for differential diagnosis of systemic lupus erythematosus based on laboratory indications
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YANG Jingyu, CHEN Liubao, WANG Kangtai, YANG Xingzhi, YU Haitao
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表1 训练集和验证集患者的6项SLE主要危险因子比较
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Tab 1 Comparison of six major risk factors for SLE in patients between training set and validation set
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| Risk factor | Training set (n=758) | Validation set (n=312) | P value |
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| SLE group | Control group | SLE group | Control group |
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| PRO | | | | | | | Pos | 227 (29.95) | 81 (10.69) | 87 (27.88) | 30 (9.62) | 0.999 | | Neg | 152 (20.05) | 298 (39.31) | 69 (22.12) | 126 (40.38) | | | Anti-dsDNA antibody (titer 1∶10) | | | | | | | Pos | 157 (20.71) | 10 (1.32) | 61 (19.55) | 5 (1.60) | 1.000 | | Neg | 222 (29.29) | 369 (48.68) | 95 (30.45) | 151 (48.40) | | | Anti-nRNP/Sm (titer 1∶100) | | | | | | | Pos | 179 (23.61) | 20 (2.64) | 51 (16.35) | 10 (3.21) | 0.274 | | Neg | 200 (26.39) | 359 (47.36) | 105 (33.65) | 146 (46.79) | | | ANA (titer 1∶100) | | | | | | | Pos | 342 (45.12) | 252(33.25) | 143 (45.83) | 108 (34.62) | 1.000 | | Neg | 37 (4.88) | 127 (16.75) | 13 (4.17) | 48 (15.38) | | | ANuA (titer 1∶100) | | | | | | | Pos | 128 (16.89) | 4 (0.53) | 52 (16.67) | 0 (0) | 1.000 | | Neg | 251 (33.11) | 375 (49.47) | 104 (33.33) | 156 (50.00) | | | Anti-P antibody (titer 1∶100) | | | | | | | Pos | 102 (13.46) | 6 (0.79) | 35 (11.22) | 2 (0.64) | 0.999 | | Neg | 277 (36.54) | 373 (49.21) | 121 (38.78) | 154 (49.36) | |
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