干扰素调节因子3促结直肠癌细胞增殖与侵袭相关探索
Exploratory study of interferon regulatory factor 3 promoting proliferation and invasion related to colorectal cancer cells
Note： Horizontal coordinates are experimental groups. A1: IRF3-WT48 h, A2: IRF3-WT72 h; B1: IRF3-5D48 h, B2: IRF3-5D72 h; C1: IRF3-2A5D48 h, C2: IRF3-2A5D72 h. Vertical coordinates are the names of the major differential genes detected at the transcriptional level. Blue via white to red indicates low to high expression; red indicates high expression genes, and blue indicates low expression genes. CDRT4—CMT1A duplicated region transcript 4; SLFN5—recombinant Schlafen family member 5; RASA4—RAS p21 protein activator 4; MALAT-1—metastasis associated in lung denocarcinoma transcript 1; TOMM6—translocase of outer mitochondrial membrane 6; BISPR—BST2 interferon-stimulated positive regulator; IFITM3—interferon-induced transmembrane protein 3; CCN3—cellular communication network factor 3; B2M—β-2 microglobulin; HELZ2—helicase with zinc finger 2; IRF9—interferon regulatory factor 9; IRF7—interferon regulatory factor 7; DDX60—DExD/H-box helicase 60; PARP9—poly (ADP-ribose) polymerase family member 9; SP110—SP110 nuclear body protein; OAS2—2′-5′-oligoadenylate synthetase 2; CMPK2—cytidine monophosphate kinase 2; RSAD2—radical S-adenosyl methionine domain containing 2; IFI27—interferon alpha-inducible protein 27; BST-2—bone marrow stromal antigen 2; PLSCR1—phospholipid scramblase 1; EPSTI1—epithelial stromal interaction 1; PARP10—poly (ADP-ribose) polymerase family member 10; REC8—REC8 meiotic recombination protein; TRIM22—tripartite motif containing 22; PNPT1—polyribonucleotide nucleotidyltransferase 1; BTK—Bruton tyrosine kinase; STAT2—signal transducer and activator of transcription 2; DTX3L—deltex E3 ubiquitin ligase 3L; HERC6—HECT and RLD domain containing E3 ubiquitin protein ligase family member 6; XAF1—XIAP-associated factor 1; DHX58—DExH-box helicase 58; APOL6—apolipoprotein L6; PRORP—protein-only RNase P catalytic subunit; CCN4—cellular communication network factor 4; SAMD9L—sterile α motif domain containing 9 like; TRIM21—tripartite-motif protein 21; DHX58—DExH-box helicase 58; ZNFX1—zinc finger NFX1-type containing 1; MATR3—matrin 3.
