香叶基香叶基焦磷酸合成酶在肺鳞状细胞癌中的表达及临床意义

王鑫, 王晓霞, 李彦庆, 郑永鑫, 乌杰, 任猛, 贾向东, 许天祥

Expression and clinical significance of geranylgeranyl diphosphate synthase1 (GGPS1) in lung squamous cell carcinoma

WANG Xin, WANG Xiaoxia, LI Yanqing, ZHENG Yongxin, WU Jie, REN Meng, JIA Xiangdong, XU Tianxiang

图7 GGPS1的PPI网络及GO、KEGG分析 Note： A/B. PPI network analysis of STRING database (A) and GeneMANIA database (B). C/D. Bubble plot of GO enrichment analysis (C) and KEGG enrichment analysis (D). MVD—mevalonate diphosphate decarboxylase; DHDDS—dehydrodolichyl diphosphate synthase subunit; PDSS1—decaprenyl diphosphate dynthase subunit 1; FNTA—farnesyltransferase, CAAX box, α; FNTB—farnesyltransferase, CAAX box, β; MVK—mevalonate kinase; PARS2—prolyl-TRNA synthetase 2, mitochondrial; SNRPE—small nuclear ribonucleoprotein polypeptide E; OMA1—OMA1 zinc metallopeptidase; HMBS—hydroxymethylbilane synthase; ZMPSTE24—zinc metallopeptidase STE24; GCH1—GTP cyclohydrolase 1; NFYA—nuclear transcription factor Y subunit α; NFYB—nuclear transcription factor Y subunit β; NFYC—nuclear transcription factor Y subunit γ; SP1—Sp1 transcription factor; NDUFAF6—NADH:ubiquinone oxidoreductase complex assembly factor 6; KCTD5—potassium channel tetramerization domain containing 5; TUSC1—tumor suppressor candidate 1.

Fig 7 PPI network and GO and KEGG analysis of GGPS1